摘要 |
<p>6-Methyl and 1,6-dimethylergoline I-derivs. R = H or a group of an aliphatic-, cycloaliphatic, aromatic- or heterocyclic carboxylic acid or sulfonic acid with 1-10 C atoms, which group may be subst. by halogen, NH2, monoalkylamino, dialkylamino, nitro, hydroxy, alkyl, alkoxy, thioether and sulfonic acid groups, R' = H or methyl The new 1,6-dimethylergoline derivs. and their related non-toxic, pharmaceutically acceptable salts have a strong biological activity, a long-lasting activity and low toxicity and are effective pain-killing agents and agents against allergies and inflammations.</p> |