摘要 |
A beclomethasone dipropionate-hexane solvate, useful in the preparation of beclomethasone dipropionate aerosols is disclosed herein. The new n-hexane solvate is stable when stored as bulk, and convenient and cheap to prepare. The trichlorofluoromethane solvate prepared by contacting micronized n-hexane solvate with trichlorofluoromethane affords beclomethasone dipropionate-trichlorofluoromethane solvate which retains its small particle size.
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