| 摘要 |
Title compds. (I, R1 = H, F, Cl, Br, I, CN; R2 = F, C1-5 alkyl hydroxyalkyl, aminoalkyl, CF3, alkoxy, CN, COOH, carbalkoxy, carbamoyl; R3 or R4 = H, C1-6 alkyl, hydroxyalkyl, alkenyl, alkinyl, substituted aralkyl) having pharmaceutical properties and suspected or protective activity against β-acceptor were prepd. by reduction of compd. II with complexed metal hydride or SnCl2(II)/HCl in solvent such as H2O, MeOH, EtOH< ethylacetate at 0-100≦̸C in the presence of catalyst such as Zn/acetic anhydride, Fe/HCl, Pt, Pd/charcoal.
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