| 摘要 |
The invention relates to preparation of synthetic macroporous ion-exchanaging materials by a ternary copolymerization of hydrophilic monomers containing non-ionogenous groups with monomers containing ionogenous groups and cross-linking monomers in an aqueous dispersion in the presence of inert components and suspension stabilizers. Hydroxyalkyl, oligoglycol and polyglycol esters and N-substituted or unsubstituted amides of acrylic and methacrylic acid are used as the hydrophilic monomers; compounds CH2=C(R)COX, where R = H or CH3, X = -OR1N(R2)R3, -OR1SO3H, -NHR1N(R2)R3 or -HNR1SO3H, R1 = alkylene and R2 and R3 = H, alkyl, hydroxyalkyl or aminoalkyl, acrylic and methacrylic acid serve as the ionogenous monomers; the crosslinking agents are selected from a group of monomers consisting of alkylene, oligoglycol or polyglycol diacrylates and dimethacrylates, alkylenebisacrylamides, alkylenebismethacrylamides, divinylbenzene and other compounds containing more than 2 polymerizable acryloyl or methacryloyl groups. The invented materials are suitable above all for isolation and chromatographic separation of sensitive compounds of the biological origin.
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