| 摘要 |
<p>A composition for medicated chewing gums having the active principle dispersed in the gum and coated by a mixture consisting of a hydrosoluble element and a water insoluble one. The principle can be one or more from the group consisting of nicotine, ibuprofen, paracetamol, D-metorfan, dimenhydrinate, ginger, 1-ascorbic acid (vitamin C), acetylcysteine, ephedrine, D-pseudoephedrine, valerian, ranitidine, chlorexidine, tibenzonium iodide, preferalby nicotine while the soluble element is a carbohydrate, preferably sorbitol and the water insoluble element is an oil, preferably hydrogenated castor oil. A process for manufacturing a tablet of medicated chewing gum having the composition according to the invention is also described. The tablet according to the invention has high stability organoleptic properties and gradual and controlled release properties.</p> |
