摘要 |
Modulating agents and methods for enhancing or inhibiting cadherin-mediated functions are provided. The modulating agents comprise at least an HAV binding motif, an analogue or peptidomimetic thereof, or an antibody or fragment thereof that specifically binds to such a motif. Modulating agents may additionally comprise one or more cell adhesion recognition sequences recognized by cadherins and/or other adhesion molecules. Such modulating agents may, but need not, be linked to a targeting agent, drug and/or support material.
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申请人 |
ADHEREX TECHNOLOGIES, INC.;DOHERTY, PATRICK;BLASCHUK, OREST, W.;GOUR, BARBARA, J. |
发明人 |
DOHERTY, PATRICK;BLASCHUK, OREST, W.;GOUR, BARBARA, J. |