发明名称 |
Combinations for HCV treatment |
摘要 |
The present invention relates a Hepatitis C virus NS3/4A protease inhibitor and a cytochrome P450 monooxygenase inhibitor. The combination acts by interfering with the life cycle of the hepatitis C virus and is therefore useful as an antiviral therapy. As such, the combination may be used for treating or preventing Hepatitis C infections in patients. The invention also relates to compositions comprising the combination of inhibitors. The invention also relates to kits and pharmaceutical packs comprising a Hepatitis C virus NS3/4A protease inhibitor and a cytochrome P450 monooxygenase inhibitor. The invention also relates to processes for preparing these compositions, combinations, kits, and packs. |
申请公布号 |
EP1944042(A1) |
申请公布日期 |
2008.07.16 |
申请号 |
EP20080102792 |
申请日期 |
2004.10.27 |
申请人 |
VERTEX PHARMCEUTICALS INCORPORATED |
发明人 |
TUNG, ROGER, D.;CHANDORKAR, GURUDATT;PERNI, ROBERT B. |
分类号 |
A61K45/00;A61K31/7056;A61K38/21;A61K45/06 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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