| 发明名称 |
IMPLANT WITH REACTIVE OXYGEN SPECIES SCAVENGING COATING |
| 摘要 |
A chronically implanted medical device is disclosed that has an outermost layer formed from a conjugate of a polymer with lipoic acid, the conjugate having free 1,2-dithiolane groups. It is contemplated that this layer scavenges reactive oxygen species, i.e. acts as an antioxidant, and thus reduces inflammation and other adverse effects around the implant itself. |
| 申请公布号 |
US2016250392(A1) |
申请公布日期 |
2016.09.01 |
| 申请号 |
US201615053532 |
申请日期 |
2016.02.25 |
| 申请人 |
Battelle Memorial Institute |
发明人 |
Sharma Gaurav;Lalgudi Ramanathan S.;Bouton Chad E. |
| 分类号 |
A61L31/10;A61L31/14 |
主分类号 |
A61L31/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An implantable device, comprising:
a substrate having a surface; and an outermost layer on the surface comprising a conjugate of a polymer with lipoic acid, the conjugate containing free 1,2-dithiolane groups. |
| 地址 |
Columbus OH US |
