| 摘要 |
A method to regulate the expression of a sequence encoding a gene using ionising radiation, wherein said method comprises the steps of: a. constructing a vector including the promoter of the X-ray inducible gene WAF1 and a sequence encoding an inducible gene the expression of which is regulated by the promoter of the X-ray inducible gene WAF1, b. delivering said vector to the target cells, tissue or organ, c. modulating the level of expression of the inducible gene(s) by providing ionising radiation suitable to cause the promoter of WAF1 to effect the expression of the sequence encoding the inducible gene. The method can be used in the treatment of tumours.
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