发明名称 |
ACTINOMYCETES PROMOTER |
摘要 |
<p>A 1 kbp length of the 5'-noncoding region of the gene encoding cytochrome P-450sca-2 in the actinomycete Streptomyces carbophilus has transcription promoter activity which is substrate inducible. When the 1 kbp region is shortened, transcription activity becomes constitutive and the shortened promoters can be used advantageously in expression systems, especially those expressing P-450sca-2 in the presence of ML-236B to produce pravastatin sodium.</p> |
申请公布号 |
HU9603300(A2) |
申请公布日期 |
1997.07.28 |
申请号 |
HU19960003300 |
申请日期 |
1996.11.29 |
申请人 |
SANKYO COMPANY LIMITED |
发明人 |
SERIZAWA,NOBUFUSA;WATANABE,ICHIRO |
分类号 |
C12N15/11;C12N1/15;C12N1/21;C12N9/02;C12N15/53;C12N15/76;C12P1/06;C12P7/62;C12R1/04;C12R1/465 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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