| 发明名称 |
UREA DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE THEREOF FOR THE TREATMENT OF DESEASES MEDIATED BY IMPDH ENZYME |
| 摘要 |
<p>The present invention relates to a novel class of compounds which are IMPDH inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.</p> |
| 申请公布号 |
HU0004421(A3) |
申请公布日期 |
2002.10.28 |
| 申请号 |
HU20000004421 |
申请日期 |
1997.04.21 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED, CAMBRIDGE, MASSACHUSETTS |
发明人 |
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| 分类号 |
A61K31/17;A61K31/18;A61K31/404;A61K31/42;A61K31/421;A61K31/422;A61P9/14;A61P29/00;A61P31/12;A61P35/00;A61P37/06;A61P43/00;C07C275/42;C07D263/18;C07D263/32;C07D277/18;C07D413/12 |
主分类号 |
A61K31/17 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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