发明名称 |
PROCESS FOR THE PREPARATION OF VORICONAZOLE AND ANALOGUES THEREOF |
摘要 |
The present invention provides a process for preparing a compound of formula: (Formula XI and XII) (XI) (XII) wherein X, Y, Z, A, B and E are as defined herein, by reacting a compound of formula: (Formula XIII) (XIII) with a compound of formula: (Formula XIV and XV) (XIV) (XV) respectively, in the presence of a transition metal catalyst, a ligand suitable for use with 15 the catalyst and a reducing agent. The invention also provides novel intermediates. |
申请公布号 |
EP2906555(B1) |
申请公布日期 |
2016.12.14 |
申请号 |
EP20130795583 |
申请日期 |
2013.10.08 |
申请人 |
Pfizer Ireland Pharmaceuticals |
发明人 |
BURRELL, Adam, James, Musgrave;O'NEILL, Padraig, Mary;PETTMAN, Alan, John |
分类号 |
C07D403/06;C07D239/30 |
主分类号 |
C07D403/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|