发明名称 TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES
摘要 The invention relates to triazole compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases: The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention, methods of using the compositions and kits thereof in the treatment of various demyelinating and neurodegenerative diseases, including multiple sclerosis.
申请公布号 WO2016197009(A1) 申请公布日期 2016.12.08
申请号 WO2016US35847 申请日期 2016.06.03
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 DAVIES, Robert, J.;CAO, Jingrong;COCKERILL, Meghan, Elise;COLLIER, Philip, Noel;DENINNO, Michael, Paul;DOYLE, Elisabeth;FRANTZ, James, Daniel;GAO, Huai;GOLDMAN, Brian, Anthony;GREY, Ronald, Lee;GRILLOT, Anne-laure;GU, Wenxin;HENDERSON, James, A.;IRARRAZAVAL, Raul Eduardo, Krauss;KOLPAK, Adrianne, Lynn;LIAO, Yusheng;MAGAVI, Sanjay Shivayogi;MALTAIS, Francois;MESSERSMITH, David;PIERCE, Albert, Charles;PEROLA, Emanuele;RYU, Elizabeth Jin-Sun;SYKEN, Joshua;WANG, Jian
分类号 A61K31/4196;A61P25/28;C07D249/14;C07D401/04;C07D401/12;C07D403/04;C07D403/14;C07D405/12;C07D405/14 主分类号 A61K31/4196
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