发明名称 |
Compositions and methods for modulating cell signaling |
摘要 |
The present invention provides growth factor-directed agents (GDAs), which act as either antagonists or agonists of cell signaling, particularly in the TGF-beta and related extracellular matrix signaling pathways. Such GDAs include monoclonal antibodies, fusion proteins and novel polypeptide compositions and/or conjugates of these compositions. |
申请公布号 |
AU2013341353(B2) |
申请公布日期 |
2017.03.16 |
申请号 |
AU20130341353 |
申请日期 |
2013.11.06 |
申请人 |
Scholar Rock, Inc.;Children's Medical Center Corporation |
发明人 |
Springer, Timothy Alan;Zon, Leonard Ira;Mahanthappa, Nagesh K. |
分类号 |
A61K39/00;A61K39/395 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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