| 主权项 |
1. An optically clear silicone hydrogel contact lens comprising:
a hydrated polymeric lens body that is the reaction product of a polymerizable composition comprising: a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and b) at least 20 wt. % of at least one HEMA-compatible polysiloxane represented by Formula (I): wherein R1 and R2 are independently selected from either hydrogen or a methyl group, X is CH2CH2O or CH2CH(OH)CH2O, k is an integer of 0 or 1, Z is a C2-C10 alkylene, m is an integer of 0 to 160, n is an integer of 1 to 75, p is an integer of 0 to 40, q is an integer of 0 to 20, h is an integer of 1 to 75, j is an integer of 0 or 1, A is O or CH2, i is an integer of 0 or 1, D is a C2-C6 alkylene optionally substituted with one or more groups selected from hydroxyl, methoxy, methyl, and ethyl, L is either methyl or a side chain that is the same as an opposite side chain on the same silicon atom as L, Q is either methyl or a side chain that is the same as an opposite side chain on the same silicon atom as Q, where the sum of m, n, and h is at least 5, wherein the HEMA-compatible polysiloxane has an HLB value of at least 5, or has a hydroxyl group content of at least 1 wt. % based on the average molecular weight of the polysiloxane, or has both an HLB value of at least 5 and has a hydroxyl group content of at least 1 wt. %, wherein the wt. % of the hydroxyalkyl methacrylate and the HEMA-compatible polysiloxane is based on the total weight of polymerizable monomers in the composition, and wherein when Z is a C3 alkylene, and when i and j are 0, then R1 is methyl and/or the at least one of p and q is at least 1, and when j is 1 and A is O, then i is 1 and R1 is methyl and/or p and q are both 0 or at least 1 or at least one of p and q is at least 2 and/or D is C3-C6 alkylene optionally substituted with one or more groups selected from hydroxyl, methoxy, methyl and ethyl. |
