发明名称 |
BIODEGRADABLE BIONANOPARTICLES FOR RELEASING THE GSE24-2 PEPTIDE, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME |
摘要 |
The invention relates to biodegradable PLGA bionanoparticles encapsulating the GSE24-2 peptide with telomerase activity, and to pharmaceutical, cosmetic and biotechnological compositions comprising same. The pharmaceutical compositions are useful for treating diseases presenting a telomerase deficiency, such as dyskeratosis congenita, and diseases presenting ageing characteristics, such as Werner syndrome, Rothmund Thompson syndrome, and other diseases where there is DNA damage such as ataxia telangiectasia. The relation also relates to the method for producing said bionanoparticles by means of a w/o/w double emulsion technique. |
申请公布号 |
EP2955224(A4) |
申请公布日期 |
2016.08.03 |
申请号 |
EP20140749363 |
申请日期 |
2014.02.03 |
申请人 |
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC);UNIVERSIDAD AUTÓNOMA DE MADRID (UAM);UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (UPV/EHU);CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS |
发明人 |
PERONA ABELLON, ROSARIO;PEDRAZ MUÑOZ, JOSE LUIS;HERNANDEZ MARTIN, ROSA MARIA;IGARTUA OLAECHEA, MANUELA;EGUSQUIAGUIRRE MARTIN, SUSANA;MANGUAN GARCIA, CRISTINA |
分类号 |
C12N9/12;A61K38/17;A61P43/00;B82Y5/00 |
主分类号 |
C12N9/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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