发明名称 |
METHOD FOR STABILIZING ANTIBODY AND STABILIZED SOLUTION-TYPE ANTIBODY PREPARATION |
摘要 |
The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of.an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody. |
申请公布号 |
EP3006463(A1) |
申请公布日期 |
2016.04.13 |
申请号 |
EP20150191413 |
申请日期 |
2004.10.01 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
UENO, YUJI;KAYASHITA, TAKASHI;ISHIHARA, ATSUSHI;NAKAKURA, MASASHI;YAMAUCHI, KYOKO |
分类号 |
C07K16/00;A61K9/00;A61K9/08;A61K39/395;A61K47/12;A61K47/18;C07K16/18;C07K16/28;C07K16/46 |
主分类号 |
C07K16/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|