| 发明名称 |
NEUTRALIZATION OF INHIBITORY PATHWAYS IN LYMPHOCYTES |
| 摘要 |
The present invention relates to methods for the treatment, prevention and diagnostic of diseases using compounds that specifically bind and inhibit human NKG2A in combination with compounds that bind and inhibit human PD-1. The invention also relates to assays to identify NKG2A+PD1+ tumor infiltrating NK and/or CD8 T cells. |
| 申请公布号 |
WO2016041945(A1) |
申请公布日期 |
2016.03.24 |
| 申请号 |
WO2015EP71069 |
申请日期 |
2015.09.15 |
| 申请人 |
INNATE PHARMA |
发明人 |
ANDRE, PASCALE;BLERY, MATHIEU;PATUREL, CARINE;WAGTMANN, NICOLAÏ |
| 分类号 |
A61K39/395;A61K39/00;A61P35/00;C07K16/28 |
主分类号 |
A61K39/395 |
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