发明名称 |
NEGATIVE SELECTION AND STRINGENCY MODULATION IN CONTINUOUS EVOLUTION SYSTEMS |
摘要 |
Strategies, systems, methods, reagents, and kits for phage-assisted continuous evolution are provided herein. These include strategies, systems, methods, reagents, and kits allowing for stringency modulation to evolve weakly active or inactive biomolecule variants, negative selection of undesired properties, and/or positive selection of desired properties. |
申请公布号 |
WO2015134121(A9) |
申请公布日期 |
2015.12.30 |
申请号 |
WO2015US12022 |
申请日期 |
2015.01.20 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LIU, DAVID, R.;CARLSON, JACOB, CHARLES;BADRAN, AHMED, HUSSEIN;ESVELT, KEVIN, MICHAEL |
分类号 |
C12N15/63;C12N9/12;C12N15/01;C12Q1/02 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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