| 主权项 |
1. A peptide of general formula (I)
R1-Wn-Xm-AA1-AA2-AA3-AA4-AA5-AA6-Yp-Zq-R2 (I) its stereoisomers, mixtures thereof and/or its cosmetic or pharmaceutical acceptable salts, wherein: AA1 is selected from the group consisting of -Phe-, -Ser-, -Trp- and -Phg-; AA2 is selected from the group consisting of -Met-, -Phe-, -Nle-, -Trp-, -Phg- and -Nva-; AA3 is selected from the group consisting of -Arg-, -Gln-, -Trp-, -Lys-, -Orn-, -His-, -Cit-, -Asn- and -Phg-; AA4 is selected from the group consisting of -Asp-, -Phe-, -Asn-, -Gln-, -Tyr-, -Trp- and -Phg-; AA5 is selected from the group consisting of -His-, -Ile-, -Orn-, -Cit-, -Nle- and -Nva-; AA6 is selected from the group consisting of -Ser-, -Val-, -Thr-, -Nle-, -Ile-, -Ala- and -Nva-; W, X, Y, Z are amino acids and are independently selected from amongst themselves; n, m, p and q are independently selected from amongst themselves and have a value of 0 or 1; n+m+p+q is smaller than 2; R1 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and R5—CO—, wherein R5 is selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, substituted or unsubstituted heterocyclyl and substituted or unsubstituted heteroarylalkyl; R2 is selected from the group consisting of —NR3R4, —OR3 and —SR3, wherein R3 and R4 are independently selected from the group consisting of H, substituted or unsubstituted non-cyclic aliphatic group, substituted or unsubstituted alicyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted heteroarylalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted aralkyl; and R1 or R2 are not α-amino acids. |
