发明名称 |
Schweinfurthins and uses thereof |
摘要 |
Disclosed is a method for preventing or treating an undesirable condition in a subject carrying cells homozygous null for the neurofibromatosis type 1 gene or subjects that are haploinsufficient for the neurofibromatosis type 1 gene, the method comprising administering to a subject in need thereof an effective amount of a schweinfurthin or schweinfurthin analog or derivative, or a pharmaceutically acceptable salt, prodrug, hydrate, or solvate thereof. Also disclosed is a new schweinfurthin compound of the formula. |
申请公布号 |
AU2010242874(B2) |
申请公布日期 |
2014.10.23 |
申请号 |
AU20100242874 |
申请日期 |
2010.04.30 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY;UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
REILLY, KARLYNE;TURBYVILLE, THOMAS;BEUTLER, JOHN A.;WIEMER, DAVID |
分类号 |
C07D311/78;A61K31/352;A61P35/00 |
主分类号 |
C07D311/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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