发明名称 Crosslinked zwitterionic hydrogels
摘要 Zwitterionic crosslinking agents, crosslinked zwitterionic hydrogels prepared from copolymerization of zwitterionic monomers with the zwitterionic crosslinking agent, methods for making crosslinked zwitterionic hydrogels, and devices that include and methods that use the crosslinked zwitterionic hydrogels.
申请公布号 US8835671(B2) 申请公布日期 2014.09.16
申请号 US201213463648 申请日期 2012.05.03
申请人 University of Washington through its Center for Commercialization 发明人 Jiang Shaoyi;Xue Hong;Carr Louisa R.
分类号 C07C69/54;A61L31/10;A61L27/52;A61K41/00;A61L29/14;C08F26/02;A61L29/08;A61L31/14;C07C229/12;A61L27/34 主分类号 C07C69/54
代理机构 Christensen O'Connor Johnson Kindness PLLC 代理人 Christensen O'Connor Johnson Kindness PLLC
主权项 1. A compound represented by the formula: wherein R1 and R2 are independently selected from the group consisting of hydrogen, fluorine, trifluoromethyl, C1-C6 alkyl, and C6-C12 aryl groups; R3 is selected from the group consisting of C1-C6 alkyl, C6-C12 aryl, CH2═C(R1)-L1-, and CH2═C(R2)-L2-; L1 and L2 are independently selected from the group consisting of —C(═O)O—(CH2)n— and —C(═O)NH—(CH2)n—, wherein n is an integer from 1 to 20; L3 is —(CH2)n—, where n is an integer from 1 to 20; A1 is C, S, SO, P, or PO; X− is the counter ion associated with the N+ cationic center; and M+ is a counterion associated with the (A1=O)O− anionic center.
地址 Seattle WA US