发明名称 AMINOPYRIMIDINONES AS INTERLEUKIN RECEPTOR-ASSOCIATED KINASE INHIBITORS
摘要 <p>This invention relates to aminopyrimidinone compounds of Formula (I) that are inhibitors of Interleukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment or prevention of inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease.</p>
申请公布号 EP2773207(A1) 申请公布日期 2014.09.10
申请号 EP20120845873 申请日期 2012.10.26
申请人 MERCK SHARP & DOHME CORP. 发明人 SEGANISH, W. MICHAEL;BRUMFIELD, STEPHANIE NICOLE;LIM, JONGWON;MATASI, JULIUS, J.;MCELROY, WILLIAM, T.;TULSHIAN, DEEN, B.;LAVEY, BRIAN, J.;ALTMAN, MICHAEL, D.;GIBEAU, CRAIG, R.;LAMPE, JOHN WILLIAM;METHOT, JOEY;ZHU, LIANG
分类号 A61K31/5377;C07D401/04;C07D413/14;C07D417/04;C07D491/08;C07D491/10 主分类号 A61K31/5377
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