发明名称 Antibody that binds to H-1 parvovirus
摘要 Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops.
申请公布号 US8828400(B2) 申请公布日期 2014.09.09
申请号 US201013513502 申请日期 2010.12.01
申请人 Deutsches Krebsforschungszentrum Siftung des Öffentlichen Rechts 发明人 Leuchs Barbara;Kürschner Kathrin;Kuck Andrea;Müller Marcus;Münstermann Silvia;Rommelaere Jean
分类号 A61K39/42;C07K16/08;C12Q1/70;G01N33/569 主分类号 A61K39/42
代理机构 Leason Ellis LLP. 代理人 Leason Ellis LLP.
主权项 1. A monoclonal antibody or an antigen binding-fragment thereof specifically binding to a full or empty H-1 parvovirus capsid, wherein said monoclonal antibody or antigen binding-fragment competes for binding with the antibody produced by the hybridoma cell line BL-H1 having the accession number ACC3030.
地址 Heidelberg DE