发明名称 |
Antibody that binds to H-1 parvovirus |
摘要 |
Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops. |
申请公布号 |
US8828400(B2) |
申请公布日期 |
2014.09.09 |
申请号 |
US201013513502 |
申请日期 |
2010.12.01 |
申请人 |
Deutsches Krebsforschungszentrum Siftung des Öffentlichen Rechts |
发明人 |
Leuchs Barbara;Kürschner Kathrin;Kuck Andrea;Müller Marcus;Münstermann Silvia;Rommelaere Jean |
分类号 |
A61K39/42;C07K16/08;C12Q1/70;G01N33/569 |
主分类号 |
A61K39/42 |
代理机构 |
Leason Ellis LLP. |
代理人 |
Leason Ellis LLP. |
主权项 |
1. A monoclonal antibody or an antigen binding-fragment thereof specifically binding to a full or empty H-1 parvovirus capsid, wherein said monoclonal antibody or antigen binding-fragment competes for binding with the antibody produced by the hybridoma cell line BL-H1 having the accession number ACC3030. |
地址 |
Heidelberg DE |