发明名称 |
METHOD OF TREATING SPINAL CORD INJURY COMPRISING ADMINISTERING METAL CHELATORS TO THE UPPER ONE-THIRD OF THE NASAL CAVITY |
摘要 |
Methods for treating the animal central nervous system against the effects of spinal cord injury, including associated cognitive, behavioral and physical impairments. Effective amounts of therapeutic agents are administered to the upper third of the patient's nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and/or copper such as iron chelators, copper chelators, and antioxidants. A particular example of a therapeutic agent is the iron chelator deferoxamine (DFO). |
申请公布号 |
US2014179787(A1) |
申请公布日期 |
2014.06.26 |
申请号 |
US201314068561 |
申请日期 |
2013.10.31 |
申请人 |
HealthPartners Research Foundation |
发明人 |
Frey, II William H.;Panter Samuel Scott;Bresin Hanson Leah Ranae |
分类号 |
A61K31/16 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Bloomington MN US |