| 摘要 |
FIELD: chemistry.SUBSTANCE: claimed are compounds of general formula I, where values of radicals are given in description, possessing inhibiting action on sodium-dependent cotransporter of glucose SGLT. Present invention also claims pharmaceutical compositions, possessing inhibiting effect with respect to SGLT, and methods of obtaining said compounds and synthetic intermediates, as well as methods of obtaining said compounds per se or in combination with other therapeutic agents for treatment of diseases or states, subjected to impact of SGLT inhibition, for instance such disease as type 1 and 2 diabetes mellitus, hyperglucemia, diabetic complications, insulin resistance, metabolic syndrome, hyperinsulinemia, hypertension, hyperuricemia, obesity, edemas, dislipidemia, chronic heart failure and atherosclerosis.EFFECT: increasing efficiency of application of derivatives.21 cl, 23 ex, 1 tbl, 8 dwg |
