10-deazaaminopterin: a new arthritis remittive drug
摘要
A double blind clinical trial of 10-deazaaminopterin versus the antirheumatoid drug methotrexate (MTX) established that 10-deazaaminopterin, in addition to being at least equally effective as methotrexate in all respects in ameliorating rheumatoid arthritis in humans, it is superior to methotrexate in controlling pain and joint stiffness and in improving grip strength. In accordance with this invention 10-deazaaminopterin is claimed as a more effective disease modifying arthritis remittive drug for the treatment of rheumatoid arthritis in humans.
申请公布号
US5030634(A)
申请公布日期
1991.07.09
申请号
US19900500911
申请日期
1990.03.29
申请人
KRUMDIECK, CARLOS L.;CASTANEDA, OSWALDO;ALARCON, GRACIELA;KOOPMAN, WILLIAM J.;NAIR, MADHAVAN G.
发明人
KRUMDIECK, CARLOS L.;CASTANEDA, OSWALDO;ALARCON, GRACIELA;KOOPMAN, WILLIAM J.;NAIR, MADHAVAN G.