发明名称 |
PYRROLO[2,3-D]PYRIMIDIN DERIVATIVES AS PROTEIN KINASE B INHIBITORS |
摘要 |
The invention relates to a compound of (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide or a pharmaceutically acceptable salt thereof, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to a pharmaceutical composition comprising said compound, using said compound in the treatment of diseases mediated by PKB and methods for preparing said compound. |
申请公布号 |
EA018512(B1) |
申请公布日期 |
2013.08.30 |
申请号 |
EA20100000552 |
申请日期 |
2008.10.09 |
申请人 |
ASTRAZENECA AB |
发明人 |
JOHNSON PAUL, DAVID;LEACH ANDREW;LUKE RICHARD, WILLIAM, ARTHUR;MATUSIAK ZBIGNEW, STANLEY;MORRIS JEFFREY, JAMES |
分类号 |
C07D487/04;A61K31/519;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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