发明名称 PYRROLO[2,3-D]PYRIMIDIN DERIVATIVES AS PROTEIN KINASE B INHIBITORS
摘要 The invention relates to a compound of (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide or a pharmaceutically acceptable salt thereof, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to a pharmaceutical composition comprising said compound, using said compound in the treatment of diseases mediated by PKB and methods for preparing said compound.
申请公布号 EA018512(B1) 申请公布日期 2013.08.30
申请号 EA20100000552 申请日期 2008.10.09
申请人 ASTRAZENECA AB 发明人 JOHNSON PAUL, DAVID;LEACH ANDREW;LUKE RICHARD, WILLIAM, ARTHUR;MATUSIAK ZBIGNEW, STANLEY;MORRIS JEFFREY, JAMES
分类号 C07D487/04;A61K31/519;A61P35/00 主分类号 C07D487/04
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