发明名称 Fremgangsmåde til krystallisation for 1-(b-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-fluorphenyl)-2- thienylmethyl]benzen
摘要 The present invention relates to a crystallization procedure to obtain 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.
申请公布号 DK2451797(T3) 申请公布日期 2013.06.24
申请号 DK20100729901T 申请日期 2010.07.08
申请人 JANSSEN PHARMACEUTICA, N.V. 发明人 RAMMELOO, THOMAS JOACHIM LANDEWALD;DE KEYSER, RUBEN;SCHILDERMANS, GUSTAAF JOZEF PETRUS
分类号 C07D309/10 主分类号 C07D309/10
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