发明名称 |
EMBODIMENTS OF A PROBE AND METHOD FOR TARGETING NUCLEIC ACIDS |
摘要 |
<p>Disclosed embodiments concern a probe comprising one or more pairs of monomers capable of targeting a nucleic acid target. The pair of monomers may be arranged in a manner that promotes thermoinstability of the probe complex, thus producing a probe capable of locating and/or detecting a target. The probe also may comprise one or more natural or non-natural nucleotides capable of Watson-Crick base pairing with an isosequential nucleic acid target. Particular disclosed embodiments concern a method of using the disclosed probe to target nucleic acids. In particular disclosed embodiments, the probe may be incubated with a target nucleic acid and then be detected.</p> |
申请公布号 |
WO2013013068(A4) |
申请公布日期 |
2013.05.30 |
申请号 |
WO2012US47442 |
申请日期 |
2012.07.19 |
申请人 |
UNIVERSITY OF IDAHO;HRDLICKA, PATRICK, J. |
发明人 |
HRDLICKA, PATRICK, J. |
分类号 |
C07D491/00;C07D471/04;C07F9/02 |
主分类号 |
C07D491/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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