| 摘要 |
The present disclosure provides methods of making and using plant extracts that include quercetin, which are generated from transgenic plants that have decreased pirin activity (prn-). Such transgenic plants and their extracts can be used to increase tolerance of a plant to a stressor, such as UV light, as well as treat tumor cells (such as kill cancer cells), prevent certain types of fungal infections (such as C. gattii), and increase antioxidant activity. The present disclosure also provides methods of making and using plant extracts that are depleted of quercetin, which are generated from transgenic plants that have increased pirin activity (prn+). Such transgenic plants and their extracts can be used to prevent certain types of fungal infections (such as C. neoformans). Also provided are compositions that include the prn- or prn+ extracts, such as a plastic coated with the extract.
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