| 摘要 |
The process involves treatment of (I): with an olefin and/or acetylene and, if necessary, using a solvent inert towards the isocyanate gp. at 30 to 250 degrees in the presence of free-radical catalysts. Using the pure enantiomers of I, in which at least R1 and R2 are different, optically active beta-halogeno-alkylisocyantes; XCR3R4CR1R2N=C=O, are formed (where X = Cl or Br; R1, R2, R3, R4 = H-atoms, satd. or unsatd. aliphatic, cycloaliphatic, aromatic or heterocyclic gps. with up to 22C atoms opt. substd. with halogen, carboxy, nitrile, nitro, alkoxy and/or arylalkoxy gps; R1 may also be COOR where R = aliphatic, cycloaliphatic or araliphatic gps.) |
