| 发明名称 |
SUBSTITUTED CYCLOALKYLIDENE COMPOUNDS |
| 摘要 |
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation. Formula (I) including salts, solvates, and pharmacologically functional derivatives thereof wherein R1is OH; each of R2 and R4 independently are selected from OH, alkyl, or halogen; each of p and q independently are selected from 0, 1, or 2; R3 is -(Y)z-R6; z is 0 or 1; Y is -C=C- or CR6=CR1-; X is -(CH2)n- where n is 0, 1, 2, or 3, -C(R9)2-, -O-,or -S-.
|
| 申请公布号 |
CA2533812(C) |
申请公布日期 |
2012.12.18 |
| 申请号 |
CA20042533812 |
申请日期 |
2004.07.27 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
BRITTON, JONATHAN E.;FANG, JING;HEYER, DENNIS;MILLER, AARON BAYNE;NAVAS, FRANK III;SMALLEY, TERRENCE LEE, JR.;ZUERCHER, WILLIAM J.;KATAMREDDY, SUBBA REDDY |
| 分类号 |
C07C59/72;A61K31/165;A61K31/192;A61K31/382;A61K31/40;A61K31/44;C07C39/23;C07C39/42;C07C43/23;C07C43/295;C07C45/45;C07C45/46;C07C45/59;C07C45/62;C07C45/67;C07C45/71;C07C47/57;C07C49/403;C07C49/83;C07C49/835;C07C49/84;C07C59/54;C07C59/56;C07C233/25;C07C235/34;C07C235/42;C07C255/13;C07C255/53;C07C311/08;C07C311/21;C07C317/22;C07D207/16;C07D207/32;C07D207/333;C07D211/60;C07D211/62;C07D213/30;C07D239/26;C07D261/08;C07D263/32;C07D295/096;C07D307/42;C07D309/20;C07D309/22;C07D335/02;C07F9/142;C07F9/40 |
主分类号 |
C07C59/72 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
