发明名称 |
LIGAND-SPECIFIC INHIBITION OF ATTACHMENT OF IMMUNE CELLS TO IMPLANTABLE BIOMATERIALS |
摘要 |
Methods for protecting biomaterials comprise attaching CD47 or Ig domain thereof to the surface of the biomaterial, thereby inhibiting or reducing immune cell attachment and/or immune cell-mediated damage to the biomaterial. Also provided are kits for practicing these methods and the protected biomaterials.
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申请公布号 |
US2012251586(A1) |
申请公布日期 |
2012.10.04 |
申请号 |
US201013262367 |
申请日期 |
2010.04.09 |
申请人 |
STACHELEK STANLEY J.;DISCHER DENNIS;LEVY ROBERT J.;TSAI RICHARD;THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
STACHELEK STANLEY J.;DISCHER DENNIS;LEVY ROBERT J.;TSAI RICHARD |
分类号 |
A61L31/10;A61K9/00;A61K38/17;A61K39/395;A61M25/00;A61N1/05;C08F8/00;C08G18/83 |
主分类号 |
A61L31/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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