发明名称 STABILIZED FORMULATIONS CONTAINING ANTI-INTERLEUKIN-6 RECEPTOR (IL-6R) ANTIBODIES
摘要 The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hlL-6R). The formulations may contain, in addition to an anti-hlL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
申请公布号 WO2011085158(A3) 申请公布日期 2012.03.22
申请号 WO2011US20457 申请日期 2011.01.07
申请人 REGENERON PHARMACEUTICALS, INC.;DIX, DANIEL, B.;GRAHAM, KENNETH, S.;KAMEN, DOUGLAS, E.;WALSH, SCOTT, M. 发明人 DIX, DANIEL, B.;GRAHAM, KENNETH, S.;KAMEN, DOUGLAS, E.;WALSH, SCOTT, M.
分类号 A61K9/08;A61K9/00;A61K31/485;A61K39/395 主分类号 A61K9/08
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