发明名称 |
Lipophilic dye-based fret assays for clostridial toxin activity |
摘要 |
Compositions useful for detecting Clostridial toxin activity comprising a cell that comprises a membrane-associated Clostridial toxin substrate comprising a first member of a fluorescence resonance energy transfer pair; and a Clostridial toxin recognition sequence including a cleavage site; and a membrane-associated second member of the FRET pair and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates. |
申请公布号 |
US8124357(B2) |
申请公布日期 |
2012.02.28 |
申请号 |
US20060908438 |
申请日期 |
2006.04.04 |
申请人 |
FERNANDEZ-SALAS ESTER;STEWARD LANCE E.;AOKI KEI ROGER;ALLERGAN, INC. |
发明人 |
FERNANDEZ-SALAS ESTER;STEWARD LANCE E.;AOKI KEI ROGER |
分类号 |
C12N5/07;C07H21/04;C12N15/74;C12Q1/37 |
主分类号 |
C12N5/07 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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