发明名称 DRUG COMBINATIONS CONTAINING PDE4 INHIBITORS AND NSAIDS
摘要 The present invention relates to new drug combinations which contain in addition to one or more PDE4-inhibitors at least one NSAID (=non-steroidal anti-inflammatory drug) (2), processes for preparing them and their use in treating in particular respiratory complaints such as for example COPD, chronic sinusitis and asthma. The invention particularly relates to those drug combinations which contain, in addition to one or more, preferably one PDE4 inhibitor of general formula 1 wherein X is SO or SO2, but preferably SO, and wherein R1, R2, R3 and R4 have the meanings given in claim 1, at least one NSAID (2), the preparation thereof and the use thereof for the treatment of respiratory complaints.
申请公布号 US2012035143(A1) 申请公布日期 2012.02.09
申请号 US201013201270 申请日期 2010.02.18
申请人 NICKOLAUS PETER;GOEGGEL ROLF;PETER DANIEL;BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 NICKOLAUS PETER;GOEGGEL ROLF;PETER DANIEL
分类号 A61K31/60;A61K31/519;A61K31/5415;A61P29/00 主分类号 A61K31/60
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