| 发明名称 |
USE OF BACTERIA FOR THE SENSING AND KILLING OF CANCER CELLS |
| 摘要 |
The present invention relates to the field of cancer therapy. Specifically, a chemotaxis fusion-receptor that directs bacteria towards tumors is disclosed. Further encompassed by the present invention is a bacterial cell that comprises at least one chemotaxis fusion-receptor and, preferably, a killing module for the destruction of tumor cells. |
| 申请公布号 |
US2011293567(A1) |
申请公布日期 |
2011.12.01 |
| 申请号 |
US200913125945 |
申请日期 |
2009.10.26 |
| 申请人 |
EILS ROLAND;HUNDESHAGEN PHILIP;REIS YARA;RICHTER DANIELA;KEIENBURG JENS;REICHENZELLER MICHAELA;FLOSSDORF MICHAEL;KENTNER DAVID;SOMMER ERIK;SOURJIK VICTOR;DI VENTURA BARBARA;BAYER PHILIP;CAI YIN;HOERNER MAXIMILIAN;KRAEMER STEPHEN;KRAEMER PASCAL;KUEHNE ANDREAS;MORITZ CHRISTIAN;RENNER MARIA;NIOPEK DOMINIK;NUSSBAUM KATHRIN;SCHLEICH KOLJA;STAHLBERG MARKUS;STOECKL ANNA;ZHU CHENCHEN;ZIESACK MARIKA;EILS ADJANA;VLADIMIROV NIKITA;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG;DKFZ DEUTCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DESOEFFENTLICHEN RECHTS |
发明人 |
EILS ROLAND;HUNDESHAGEN PHILIP;REIS YARA;RICHTER DANIELA;KEIENBURG JENS;REICHENZELLER MICHAELA;FLOSSDORF MICHAEL;KENTNER DAVID;SOMMER ERIK;SOURJIK VICTOR;DI VENTURA BARBARA;BAYER PHILIP;CAI YIN;HOERNER MAXIMILIAN;KRAEMER STEPHEN;KRAEMER PASCAL;KUEHNE ANDREAS;MORITZ CHRISTIAN;RENNER MARIA;NIOPEK DOMINIK;NUSSBAUM KATHRIN;SCHLEICH KOLJA;STAHLBERG MARKUS;STOECKL ANNA;ZHU CHENCHEN;ZIESACK MARIKA;EILS ADJANA;VLADIMIROV NIKITA |
| 分类号 |
C12N15/62;A61K48/00;A61P35/04;C07K14/435;C12N1/21;C12N15/63 |
主分类号 |
C12N15/62 |
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