发明名称 3′-ethynylcytidine derivative
摘要 To provide a compound which exhibits excellent anti-tumor activity and excellent oral absorption and which is a useful anti-tumor drug. The invention provides a 3′-ethynylcytidine derivative represented by formula (1): (wherein X represents a (substituted) alkylcarbonyl group, a (substituted) alkoxycarbonyl group, or a hydrogen atom; one of Y and Z represents a hydrogen atom or a group represented by (R1)(R2)(R3)Si— and the other represents a group represented by (R4)(R5)(R6)Si—; and R1, R2, R3, R4, R5, and R6 each represent a (substituted) alkyl group, a (substituted) cyclic alkyl group, or a (substituted) aryl group) or a salt thereof.
申请公布号 US8058261(B2) 申请公布日期 2011.11.15
申请号 US20070375077 申请日期 2007.07.23
申请人 TANAKA MOTOAKI;FUKUSHIMA MASAKAZU;TAIHO PHARMACEUTICAL CO., LTD. 发明人 TANAKA MOTOAKI;FUKUSHIMA MASAKAZU
分类号 A01N43/04;A61K31/70 主分类号 A01N43/04
代理机构 代理人
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