Disclosed is a pacemaker cell derived from an embryonic stem cell (ES cell) or an induced pluripotent stem cell (iPS cell), that is provided with an HCN4 channel and an Na channel and is capable of controlling heart rates by controlling the Na channel. Also disclosed is a cardiac pacemaker that comprises the abovementioned pacemaker cell.
申请公布号
WO2011040469(A1)
申请公布日期
2011.04.07
申请号
WO2010JP66952
申请日期
2010.09.29
申请人
NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY;HISATOME, ICHIRO;SHIRAYOSHI, YASUAKI;MIAKE, JUNICHIRO