METHODS FOR THE ANALYSIS OF PROXIMITY BINDING ASSAY DATA
摘要
<p>Various embodiments of methods for analyzing proximity binding assay (PBA) data are disclosed. Proximity binding assays as a class of analyses offer the advantages of the sensitivity and specificity of biorecognition binding, along with the exponential signal amplification offered by a variety of oligonucleotide amplification reactions, such as the polymerase chain reaction (PCR). However, as various proximity binding assays have reaction kinetics governed by an additional step of the binding of a biorecognition probe (BRP) with a target molecule, there is a need for methods for the analysis of PBA data that are particularly suited to the unique characteristics of such data.</p>
申请公布号
WO2011017567(A1)
申请公布日期
2011.02.10
申请号
WO2010US44615
申请日期
2010.08.05
申请人
LIFE TECHNOLOGIES CORPORATION;CHEN, SHIAW-MIN;RUFF, DAVID, W.;LEONG, HARRISON, M.
发明人
CHEN, SHIAW-MIN;RUFF, DAVID, W.;LEONG, HARRISON, M.