发明名称 METHODS AND SYSTEMS FOR MULTI-ANTIBODY THERAPIES
摘要 The present invention relates to methods and systems for administering antibody therapeutic agents. The methods include administering one or more (e.g., two or three) binding agents, wherein each of the binding agents has a binding region that is specific to a portion of a disease agent and one or more copies of a tag. The binding agents can be specific to one or more portions of the same or different disease agents. The tag is the same for each of the binding agents. The methods include administering an anti-tag antibody, wherein the anti-tag antibody has an anti-tag region that is specific to the tag, and can have an immunoglobulin (e.g., IgA, IgD, IgE, IgG, and IgM.). Disease agents include bacterial proteins, viral proteins, cancer cells, and proteins or toxins produced therefrom. In particular, the present invention includes methods and systems for binding agents that are specific to neurotoxins that cause botulism.
申请公布号 US2010278830(A1) 申请公布日期 2010.11.04
申请号 US20080032744 申请日期 2008.02.18
申请人 发明人 SHOEMAKER CHARLES B.;SEPULVEDA TOEPFER JORGE A.;MUKHERJEE JEAN
分类号 A61K39/395;A61K38/16;A61K39/40;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P35/04;C07K14/00;C12N5/10;C12N15/63 主分类号 A61K39/395
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