发明名称 |
Use of acacetin and related compounds as potassium channel inhibitors |
摘要 |
This invention provides a method for treating or preventing human atrial arrhythmia (fibrillation) using the leading flavone compound acacetin, and its derivatives and analogues that inhibit the ultra-rapidly-activating delayed rectifier potassium current (IKur or IKsus), transient outward potassium (Ito), and acetylcholine-activated potassium current (IK.ACh).
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申请公布号 |
US7816400(B2) |
申请公布日期 |
2010.10.19 |
申请号 |
US20080039921 |
申请日期 |
2008.02.29 |
申请人 |
THE UNIVERSITY OF HONG KONG;SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES |
发明人 |
LI GUI-RONG;LAU CHU-PAK;QIN GUO-WEI;WANG HONG-BING |
分类号 |
A61K31/352;A61P9/06 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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