发明名称 |
PROCESSES FOR THE SYNTHESIS OF LEVOCETIRIZINE AND INTERMEDIATES FOR USE THEREIN |
摘要 |
The present invention provides a compound of formula (IV) wherein R is Cl, Br, NO2, OH or OR', and R' is alkyl, and its use in the synthesis of levocetirizine, including its use in the synthesis of (-)-1-[(4-chlorophenyl)-phenyl methyl] piperazine, an intermediate useful in the synthesis of levocetirizine. The present invention also provides compounds (II) and (III) which are useful in the synthesis of compound (IV). |
申请公布号 |
WO2009147389(A3) |
申请公布日期 |
2010.07.01 |
申请号 |
WO2009GB01385 |
申请日期 |
2009.06.02 |
申请人 |
CIPLA LIMITED;RAO, DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;GHAGARE, MARUTI;CHIKHALIKAR, SANDIP VASANT;CURTIS, PHILIP, ANTHONY |
发明人 |
RAO, DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;GHAGARE, MARUTI;CHIKHALIKAR, SANDIP VASANT;CURTIS, PHILIP, ANTHONY |
分类号 |
C07D295/088;C07C27/00;C07D295/073;C07D295/096 |
主分类号 |
C07D295/088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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