摘要 |
<p>The present invention relates to a method of screening for a modulator of endothelial NO synthase (eNOS) expression, a method of diagnosing a cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament for preventing and/or treating a disease involving eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of eNOS signal transduction, and the use of HEBP1 for the regulation of eNOS promoter activity.</p> |
申请人 |
SANOFI-AVENTIS;KRUG, ALEXANDRA;KRUIP, JOCHEN;WOHLFART, PAULUS;GASSENHUBER, JOHANN;HEERMEIER, KATHRIN;STROBEL, HARTMUT;KARST, NATALIE;FERRIER, ALEXANDRA;VISKOV, CHRISTIAN |
发明人 |
KRUG, ALEXANDRA;KRUIP, JOCHEN;WOHLFART, PAULUS;GASSENHUBER, JOHANN;HEERMEIER, KATHRIN;STROBEL, HARTMUT;KARST, NATALIE;FERRIER, ALEXANDRA;VISKOV, CHRISTIAN |