发明名称 |
Proanthocyanidins for the Treatment of Amyloid and Alpha-Synuclein Diseases |
摘要 |
A method of treating an amyloid disease, or a disease characterized by alpha-synuclein or NAC fibrillogenesis, in a mammalian subject. The method includes administering to the mammal a therapeutically effective amount of a various disclosed proanthocyanidins or a proanthocyanidin characterized by disclosed general formulae. A pharmaceutical composition comprising a therapeutically effective amount of a proanthocyanidin and a pharmaceutically acceptable excipient. The therapeutic amount of the proanthocyanidin is selected for efficacy in treating amyloid, alpha-synuclein or NAC fibrillogenesis in a mammalian subject.
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申请公布号 |
US2010010079(A1) |
申请公布日期 |
2010.01.14 |
申请号 |
US20090470374 |
申请日期 |
2009.05.21 |
申请人 |
SNOW ALAN D;CASTILLO GERARDO M;CHOI PAULA Y;NGUYEN BETH P |
发明人 |
SNOW ALAN D.;CASTILLO GERARDO M.;CHOI PAULA Y.;NGUYEN BETH P. |
分类号 |
A61K31/352;A61K31/215;A61K31/353;A61K31/357;A61K31/7048;A61K36/74;A61K45/06;A61P25/28 |
主分类号 |
A61K31/352 |
代理机构 |
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地址 |
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