发明名称 |
IMPROVED YEAST STRAIN FOR PRODUCTION OF FOUR CARBON ALCOHOLS |
摘要 |
<p>Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol.</p> |
申请公布号 |
WO2009140159(A1) |
申请公布日期 |
2009.11.19 |
申请号 |
WO2009US43275 |
申请日期 |
2009.05.08 |
申请人 |
E. I. DU PONT DE NEMOURS AND COMPANY;LAROSSA, ROBERT, A. |
发明人 |
LAROSSA, ROBERT, A. |
分类号 |
C12N15/09;C12P7/16;C12R1/01 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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