| 摘要 |
Disclosed in a process for making (1) a compound of the formula NC-CH<SUB>2</SUB>-CH<SUB>2</SUB>-CH<SUB>2</SUB>-CH<SUB>2</SUB>-CO<SUB>2</SUB>R', wherein R' is H or C<SUB>1 </SUB>to C<SUB>12 </SUB>alkyl, or (2) adipic acid or (3) dimethyl adipate, using as the substrate, 3-pentenenitrile, (2) 3-pentenoic acid or methyl 3-pentenoate, respectively, by contacting the substrate with carbon monoxide and a nucleophile in the presence of a Group VIII metal, a selected ligand, and an acid promoter. The nucleophile, which (a) an alcohol or water, or (b) water or (c) methanol, respectively, in the presence of a Group VIII metal, preferably palladium, a selected phosphine ligand, and an acid promoter.
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