发明名称 |
METHOD FOR SOLUBILIZING METRONIDAZOLE |
摘要 |
<p>Solubilizing metronidazole comprises mixing an aqueous phase of metronidazole with glycolic niacinamide or its salts and at least two glycolic co-solvents, in the absence of cyclodextrin. Independent claims included for: (1) an aqueous metronidazole solution and obtained by the process; (2) an aqueous solution of metronidazole and niacinamide obtained by the process comprising at least two glycolic co-solvents; and (3) a pharmaceutical composition comprising the solution. - ACTIVITY : Dermatological. - MECHANISM OF ACTION : None given.</p> |
申请公布号 |
EP1896016(A2) |
申请公布日期 |
2008.03.12 |
申请号 |
EP20060778604 |
申请日期 |
2006.06.16 |
申请人 |
GALDERMA S.A. |
发明人 |
MALLARD, CLAIRE;BRZOKEWICZ, ALAIN |
分类号 |
A61K31/4164;A61K9/08;A61K47/22;A61P17/00 |
主分类号 |
A61K31/4164 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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