发明名称 |
NOVEL PIPERIDINE DERIVATIVE |
摘要 |
Disclosed is a substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on the activity which a histamine H3 receptor constantly exhibits. A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R1 represents a phenyl group which may be substituted or the like and R2 represents a cyano group which may be substituted or the like, or R1 and R2 together form an aliphatic hetetocyclic ring which may be substituted; R3 represents a group represented by the formula (II-1) below; and all of X1 to X4 represent a carbon atom or the like: (II-1) where R4 and R5 represent a lower alkyl group or the like; and m1 represents an integer of 2 to 4. |
申请公布号 |
KR20080013986(A) |
申请公布日期 |
2008.02.13 |
申请号 |
KR20077028146 |
申请日期 |
2006.05.29 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIKAWA SHIHO;SATO NAGAAKI;NAGASE TSUYOSHI;TOKITA SHIGERU;WADA TOSHIHIRO;TAKAHASHI HIDEKAZU |
分类号 |
C07D211/22;A61K31/438;A61K31/444;C07D498/10 |
主分类号 |
C07D211/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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