发明名称 NOVEL PIPERIDINE DERIVATIVE
摘要 Disclosed is a substance having an antagonistic effect on the binding of histamine to a histamine H3 receptor or an inhibitory effect on the activity which a histamine H3 receptor constantly exhibits. A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein R1 represents a phenyl group which may be substituted or the like and R2 represents a cyano group which may be substituted or the like, or R1 and R2 together form an aliphatic hetetocyclic ring which may be substituted; R3 represents a group represented by the formula (II-1) below; and all of X1 to X4 represent a carbon atom or the like: (II-1) where R4 and R5 represent a lower alkyl group or the like; and m1 represents an integer of 2 to 4.
申请公布号 KR20080013986(A) 申请公布日期 2008.02.13
申请号 KR20077028146 申请日期 2006.05.29
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 ISHIKAWA SHIHO;SATO NAGAAKI;NAGASE TSUYOSHI;TOKITA SHIGERU;WADA TOSHIHIRO;TAKAHASHI HIDEKAZU
分类号 C07D211/22;A61K31/438;A61K31/444;C07D498/10 主分类号 C07D211/22
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